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Academic Journal of Health A Case Report: Pyoderma Gangrenosum, Acne and Hidradenitis Suppurativa (PASH) Syndrome [Acad J Health]
Acad J Health. 2023; 1(2): 47-49 | DOI: 10.14744/ajh.2023.18209

A Case Report: Pyoderma Gangrenosum, Acne and Hidradenitis Suppurativa (PASH) Syndrome

Tuğba Atak, Selda Pelin Kartal
Department of Dermatology, Ankara Etlik City Hospital, Ankara, Türkiye

PASH syndrome, consisting of the triad of pyoderma gangrenosum (PG), acne, and hidradenitis suppurativa (HS), is a rare chronic autoinflammatory disease. The etiology and pathogenesis of the syndrome are not yet clearly understood. However, certain genes, such as PSTPIP1, have been associated with this syndrome. In treating PASH syndrome, various options are available depending on the disease’s severity, including recommendations for weight loss and smoking cessation. Furthermore, there is a rare possibility of cutaneous malignancy developing in HS, a component of PASH syndrome, which tends to worsen the prognosis for these patients. In HS patients, distinguishing between malignant transformation in chronic lesions and classical lesions is challenging, potentially leading to diagnostic delays. Therefore, in high-risk patients with long-standing atypical ulcerative lesions, malignancy should be suspected. This case report presents a 46-year-old male patient diagnosed with PASH syndrome.

Keywords: Acne, hidradenitis suppurativa, pyoderma gangrenosum, treatment

Tuğba Atak, Selda Pelin Kartal. A Case Report: Pyoderma Gangrenosum, Acne and Hidradenitis Suppurativa (PASH) Syndrome. Acad J Health. 2023; 1(2): 47-49

Corresponding Author: Tuğba Atak, Türkiye
Manuscript Language: English