Multi-modality Imaging of Persistent Left Superior Vena Cava in Patients with Sinus Venosus Type of Atrial Septal Defect and Partial Pulmonary Venous Return

Sinus venosus type atrial septal defects (ASD) are a rare subtype of ASD. These defects commonly coexist with a partial anomalous pulmonary venous return. However, the association between sinus venosus type ASD and persistent left superior vena cava is scarcely documented in the literature. We present a case of a 30-year-old woman who reported weakness and shortness of breath. A transthoracic echocardiogram indicated right heart chamber dilatation and an enlarged coronary sinus. Subsequent transesophageal echocardiography with 2D and 3D views, computed tomography, and right cardiac catheterization confirmed the coexistence of a persistent left superior vena cava, sinus venosus type of atrial septal defect, and partial anomalous pulmonary venous return.