Primary yolk sac tumor of the liver is a highly infrequent category of germ cell tumors, especially in adults. Therefore, it is critical to differentiate the disease from more common hepatic cancers that are also characterized by high serum alpha-fetoprotein (AFP) levels, such as hepatocellular carcinoma and hepatoblastoma. We report a male patient in his early 30s who presented with abdominal pain, elevated serum AFP concentration, and a cystic mass on the liver. The patient underwent two lines of chemotherapeutic treatment. We discuss adult patients with primary yolk sac tumors of the liver and the management of their condition in the literature.
Keywords: Liver, tumor, yolk sac